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Cyanocobalamin is a compound that is metabolized to a in the commonly known as vitamin B 12 or B12 for short. The name vitamin B 12 is used in two different ways.
In a broad sense it refers to a group of cobalt containing compounds known as cobalamins - cyanocobalamin (an artifact formed as a result of the use of Cyanide in the purification procedures), Hydroxocobalamin and the two coenzyme forms of B12 Methylcobalamin B12 and 5-deoxyadenosylcobalamin B12. In a more specific way, the term B12 is used to refer to only one of these forms, cyanocobalamin, which is the principal B12 form used for foods and in nutritional supplements.
The only Sublingual vitamin that all doctors recommend is vitamin B12, you must have enough of it for your bodies metabalism. Sublinqual Vitamin B12 Bottle has 100 Tablets Wow! These B-12 tablets differ from most other because they are sublinqual.
There are 100 tablets in every bottle and are reccomended to be taken once a day. Vitamin B12 : Vitamin B12 is a group of cobalt-containing B complex vitamins, also known as cobalamins, synthesized by microorganisms. Cyanocobalamin the principal form of vitamin B12 in clinical use.
In man, an exogenous source is required for nucleoprotein and myelin synthesis, cell production, normal growth, and for the maintenance of normal erythropoiesis.
Pseudo-B12 refers to B12 -like substances which are found in certain organisms; however, these substances do not have B12 biological activity for humans.
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Sublinqual (under tongue) Vita B-12
B12 Vitamin Cyanocobalimin
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Low B12 intake can lead to blood and metabolic problems, particularly in lactating mothers or diabetics: pernicious anemia, neurological disorders, problems in fat metabolism and red blood cell synthesis. Many vegetarians may not be getting adequate amounts of cyanocobalamin B12.
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MULTIPLE SCLEROSIS and VITAMIN B12 DEFICIENCY
| MULTIPLE SCLEROSIS and VITAMIN B12 DEFICIENCY |
The etiology of multiple sclerosis is unknown, although it is widely believed to be associated with a viral or immunologic cause. Vitam B12 deficiency, although associated with several neurologic complications, has not previously been reported in association with multiple sclerosis. However, Reyolds* and colleagues report 10 cases in Great Britain in which an unusual vitamin B12 deficiency occured in association with multiple sclerosis.
The 10 patients (seven women and three men) ranged in age from 27 to 51 years at the onset of neurologic disease, and all presented with the typical clinical features of multiple sclerosis. Magnetic resonance imaging performed in seven of the patients revealed multiple lesions in the white matter consistent with multiple sclerosis. Vitamin B12 deficiency, although unusual in patients under 40, was present before this age in eight of the patients.
Results of electromyograms revealed no peripheral neuropathy, although this is the most common neurologic manifestation of vitamin B12 deficiency.
Nine of the patients had serum vitamin B12 levels below 203 pg per mL (150 pmol per L). The cause of the vitamin deficiency was unknown in most of the patients. Only two of the patients were anemic, and only two of the patients had pernicious anemia. None of the patients had gastrointestinal disease or had previously undergone gastrectomy. Eight patients had macrocytosis.
Large-scale studies conducted in the early 1960s did not demonstrate an association between multiple sclerosis and low levels vitamin B12 in serum and cerebrospinal fluid. However, the authors conclude that there may be an association between vitamin B12 deficiency and multiple sclerosis that is more than coincidental.
Further studies of vitamin B12 metabolism, binding and transport in patients with multiple sclerosis are indicated.
* (Reynolds, T. et al "M.S. & Vit B12 Deficiency" American Family Physician 44, 2168)
(Archives of Neurology, August 1991, vol. 48, p.808)
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