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Cyanocobalamin is a compound that is metabolized to a in the commonly known as vitamin B 12 or B12 for short. The name vitamin B 12 is used in two different ways.

In a broad sense it refers to a group of cobalt containing compounds known as cobalamins - cyanocobalamin (an artifact formed as a result of the use of Cyanide in the purification procedures), Hydroxocobalamin and the two coenzyme forms of B12 Methylcobalamin B12 and 5-deoxyadenosylcobalamin B12. In a more specific way, the term B12 is used to refer to only one of these forms, cyanocobalamin, which is the principal B12 form used for foods and in nutritional supplements.

The only Sublingual vitamin that all doctors recommend is vitamin B12, you must have enough of it for your bodies metabalism. Sublinqual Vitamin B12 Bottle has 100 Tablets Wow! These B-12 tablets differ from most other because they are sublinqual.

There are 100 tablets in every bottle and are reccomended to be taken once a day. Vitamin B12 : Vitamin B12 is a group of cobalt-containing B complex vitamins, also known as cobalamins, synthesized by microorganisms. Cyanocobalamin the principal form of vitamin B12 in clinical use.

In man, an exogenous source is required for nucleoprotein and myelin synthesis, cell production, normal growth, and for the maintenance of normal erythropoiesis.


Pseudo-B12 refers to B12 -like substances which are found in certain organisms; however, these substances do not have B12 biological activity for humans.


"Gentlemen: The 1,000mcg oral B-12, Natural Brand are making my day! Taking 3 or 4 in the morning and if needed, 2 or 3 in the afternoon. Keeps my energy level up, makes me feel great, and calms my nerves. The terrific part - its all natural B-12 crystals! Glad I found you. Thanks Again! Your grateful customer," Signed, C. Bosick


Sublinqual (under tongue) Vita B-12
B12 Vitamin Cyanocobalimin
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Low B12 intake can lead to blood and metabolic problems, particularly in lactating mothers or diabetics: pernicious anemia, neurological disorders, problems in fat metabolism and red blood cell synthesis. Many vegetarians may not be getting adequate amounts of cyanocobalamin B12.


Natural Brand B-12 vitab12.com
Natural Brand B-12 vitab12.com
Cyanocobalamin is a compound that is metabolized to a in the commonly known as vitamin B 12 or B12 for short. The name vitamin B 12 is used in two different ways. In a broad sense it refers to a group of cobalt containing compounds known as cobalamins - cyanocobalamin (an artifact formed as a result of the use of Cyanide in the purification procedures), Hydroxocobalamin and the two coenzyme forms of B12 Methylcobalamin B12 and 5-deoxyadenosylcobalamin B12. In a more specific way, the term B12 is used to refer to only one of these forms, cyanocobalamin, which is the principal B12 form used for foods and in nutritional supplements.
VITAMIN B12 cyanocobalimin

VITAMIN B12 cyanocobalimin


Vitamin B-12 (cobalamin), stored in the liver, is a cofactor for two coenzymes. Methyl-cobalamin catalyzes methyl group transfer from a folic acid cofactor to form methionine; the unmethylated folate cofactor then participates in single carbon reactions for nucleic acid synthesis. Thus some B-12 and folic deficiency symptoms are similar. The B-12 coenzyme deoxyadenosylcobalamin catalyzes amino acid and fatty acid breakdown.

Deficiencies: Stages of deficiency symptoms include Stage I (early deficiency), lower serum holoTC II (<60 pg/mL); Stage II, lower serum vitamin B-12 (<300 pg/mL) and holoTC II (<40 pg/mL); Stage III, serum B-12 <200 and holoTC II <40 pg/mL, neutrophil hypersegmentation, elevated serum and urinary methylmalonic acid and homocysteine; and Stage IV (severest deficiency), also megaloblastic, macrocytic anemia. Around Stage III (before anemia), potentially irreversible demyelination of spinal cord, brain, and optic and peripheral nerves produces peripheral neuropathy progressing to subacute combined degeneration. Dementia, poor attention span, and depression may be early symptoms.

The stomach secretes intrinsic factor that binds B-12 and mediates its absorption at receptor sites in the ileum. Inadequate intrinsic factor secretion occurs in pernicious anemia, an autoimmune disease. In the elderly, atrophic gastritis is commonly associated with B-12 malabsorption and deficiency. Because the absorbed vitamin is secreted in bile and subsequently reabsorbed, deficiency symptoms can take 20 years to develop from low intakes, e.g., in strict vegetarians. However, in malabsorption, deficiency occurs in months or a few years because absorption from both the diet and enterohepatic circulation is impaired.

Diet recommendations: The Recommended Daily Allowances (RDAs) are (µg/day): 0.3 at age 0-6 months, 0.5 for 6-12 months, 0.7 for 1-3 years, 1.0 for 4-6 years, 1.4 for 7-10 years, 2.0 for adolescents and adults, 2.2 in pregnancy and 2.6 in lactation. Usual intakes are about 4-8 µg/d. Pregnant, lactating, and long-term strict vegetarians should take supplements providing the RDA.

Food sources: Vitamin B-12 is found only in animal products. Excellent sources (>10 µg/100g) include organ meats and bivalve mollusks such as clams and oysters. Moderate amounts (1-10 µg/100g) are contained in egg yolks, muscle meats and poultry, fish, fermented cheeses and dry milk. Milk and milk products contain <1 µg/100g. There is no human-active form of B-12 in algae such as nori and spirulina; the forms are all analogues.

Toxicity: No toxic effects have been reported when up to 100 µg/day are consumed. Intramuscular injections of 100 µg are usually given once/month to individuals who cannot absorb the vitamin through their intestine, because of pernicious anemia or other problems.

Recent research: Vitamin B-12 deficiency may increase the risk of neural tube defects in pregnant women with a high risk of this condition. Vitamin B-12 deficiency may be common in developing countries, perhaps due to malabsorption and low intakes.

For further information:

Herbert, V. (1996) Vitamin B-12. In: Present Knowledge in Nutrition (Ziegler, E. E. & Filer, L. J., Jr., eds.), 7th ed., pp. 191-205. International Life Sciences Institute Press, Washington, DC. Allen, L. H. & Casterline, J. (1994) Vitamin B-12 deficiency in the elderly: diagnosis and requirements. Am. J. Clin. Nutr. 60: 12-14.

Prepared By:

Lindsay Allen, Ph.D. Professor, Department of Nutrition University of California at Davis Meyer Hall Davis, CA 95616-8669 Phone: 530-752-5920 FAX:530-752-3406

Email: lhallen@ucdavis.edu

Victor D. Herbert, M.D., J.D. Professor Hematology and Nutrition Lab Bronx VA Medical Center (151E) 130 W Kingsbridge Road Bronx, NY 10468-3904 Phone: 718-364-5799 FAX: 718-562-9120

Email: nutristar@aol.com


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